Oct 21

Drug distributors and Teva reach settlement in Ohio opioid litigation – WSJ

The logo of Teva Pharmaceutical Industries is seen during a news conference hold by its CEO, Kare Schultz, to discuss the company’s 2019 outlooks in Tel Aviv, Israel February 19, 2019. REUTERS/Amir Cohen (Reuters) – McKesson Corp, Cardinal Health Inc, AmerisourceBergen Corp and Teva Pharmaceutical Industries reached a settlement with two Ohio counties related to the opioid crisis, the Wall Street Journal reported on Monday, citing sources. Walgreens Boots Alliance had not yet reached a deal Monday morning, the WSJ reported. (on.wsj.com/33IU2sy) Reporting by Manas Mishra in Bengaluru; Editing by Shinjini Ganguli Our Standards:The Thomson Reuters Trust Principles.

Oct 21

Reckoning with U.S. opioid crisis as $8 billion Ohio trial kicks off

CLEVELAND (Reuters) – The fight over who is responsible for the opioid epidemic that has ravaged the United States heads to court on Monday in Ohio as local governments seek billions of dollars from companies that manufactured and distributed the highly-addictive painkillers. A sign is seen on the outside of the courtroom on the first day of a trial of Johnson & Johnson over claims they engaged in deceptive marketing that contributed to the national opioid epidemic in Norman, Oklahoma, U.S. May 28, 2019. REUTERS/Nick Oxford The trial will pit two Ohio counties against five companies the local governments say helped fuel a nationwide crisis. Some 400,000 U.S. overdose deaths between 1997 and 2017 were linked to opioids, according to government data. Ohio’s Cuyahoga and Summit counties are seeking around $8 billion to pay for addiction treatment programs and to … Continue reading

Oct 21

Factbox: Billion-dollar lawsuits accuse drugmakers, distributors of fueling U.S. opioid crisis

(Reuters) – On Monday, two Ohio counties will face off in a U.S. courtroom with five companies they accuse of fueling the nationwide opioid epidemic. The counties are seeking billions of dollars to cover the cost of addiction treatment programs, healthcare and other services. FILE PHOTO: A pharmacist refills a container in a drug dispensing machine at the Rock Canyon pharmacy in Provo, Utah, U.S., May 9, 2019. REUTERS/George Frey Opioids were involved in almost 400,000 overdose deaths in the United States from 1999 to 2017, according to the U.S. Centers for Disease Control and Prevention. The following is a summary of where and how the opioid litigation is playing out across the United States: ** Ohio’s Cuyahoga and Summit counties are seeking around $8 billion from the three largest U.S. drug distributors – McKesson Corp, AmerisourceBergen Corp and Cardinal … Continue reading

Oct 21

Factbox: The U.S. opioid epidemic by the numbers

(Reuters) – Opioid deaths in the United States have soared over the last two decades, driving a wave of litigation against drugmakers and distributors. FILE PHOTO: A bottle of prescription painkiller OxyContin, 40mg pills, made by Purdue Pharma L.D. sit on a counter at a local pharmacy, in Provo, Utah, U.S., April 25, 2017. REUTERS/George Frey/File Photo The following is a look at the scale of the epidemic and the related legal battles. Numbers relating to opioid use, illnesses and deaths are based on information from the U.S. Centers for Disease Control and Prevention. ** Deaths linked to overdoses of opioids in U.S., including illegal drugs like heroin, from 1990 to 2017: nearly 400,000 ** Number of those deaths linked to prescription opioids: about 218,000 ** Average number of opioid overdose deaths in the United States per day: about 130 … Continue reading

Oct 21

Timeline: Popular heartburn medicine Zantac pulled off store shelves

(Reuters) – The U.S. Food and Drug Administration and international health authorities are investigating the safety of Zantac heartburn medicine, also sold generically as ranitidine, after finding a probable cancer-causing impurity in the drug. Zantac heartburn pills are seen in this picture illustration taken October 1, 2019. REUTERS/Brendan McDermid/Illustration Ranitidine is the newest drug in which presence of cancer causing impurities have been found. Regulators have been recalling some blood pressure and heart failure medicines since last year. The following is a timeline on Zantac: 1983 Glaxo Holdings Ltd, now a part of GlaxoSmithKline PLC, receives its first U.S. FDA approval for Zantac as a short-term treatment of a common form of ulcers. The drug was already approved in 31 different countries. 1988 Zantac becomes the world’s best selling drug and one of the first-ever drugs to top $1 billion … Continue reading

Oct 21

GSK to sell two vaccines in $1.1 billion deal to focus on newer treatments

FILE PHOTO: The GlaxoSmithKline (GSK) logo is seen on top of GSK Asia House in Singapore, March 21, 2018. REUTERS/Loriene Perera/File Photo (Reuters) – GlaxoSmithKline will sell two travel vaccines to Bavarian Nordic for up to 955 million euros ($1.1 billion), the British firm said on Monday, as it looks to bolster its push into the lucrative cancer drug market. The sale of anti-rabies treatment Rabipur and Encepur, used for the prevention of tick-borne encephalitis, to the Denmark-based biotechnology firm includes an upfront payment of 301 million euros and milestone payments of up to 495 million euros. Chief Executive Officer Emma Walmsley has been pushing for a leaner structure since she took over in 2017 by spinning off or selling units to focus on reinvigorating GSK’s pharmaceuticals business. It staged a comeback into cancer treatments with a $5.1 billion buyout … Continue reading

Oct 21

Roche pushes late-comer Tecentriq as new liver cancer option

FILE PHOTO: Swiss drugmaker Roche’s logo is seen at their headquarters in Basel, Switzerland January 28, 2016. REUTERS/Arnd Wiegmann/File Photo ZURICH (Reuters) – Roche’s Tecentriq mixed with Avastin helped liver cancer patients live longer, a boost to the Swiss drugmaker’s strategy of expanding its late-to-the-game immunotherapy into niche areas not yet dominated by rivals. Roche said on Monday it will submit overall and progression-free survival data in hepatocellular carcinoma to U.S., European and Chinese regulators in hopes of a speedy approval. The study compared Tecentriq and Avastin with sorafenib, the generic name for Bayer’s Nexavar. Tecentriq’s revenue, while growing, pales in comparison to Keytruda from Merck and Opdivo from Bristol-Myers Squibb, doctors’ go-to immunotherapies for lucrative areas such as non-small cell lung cancer. But Roche’s drug is gaining a foothold against smaller targets including triple-negative breast cancer, where it has … Continue reading

Oct 21

GSK to sell two travel vaccines to Danish biotech firm

FILE PHOTO: The GlaxoSmithKline (GSK) logo is seen on top of GSK Asia House in Singapore, March 21, 2018. REUTERS/Loriene Perera/File Photo (Reuters) – GlaxoSmithKline Plc said on Monday it will sell two travel vaccines to Denmark-based biotechnology company Bavarian Nordic for an upfront payment of 301 million euros ($335.71 million). The sale of anti-rabies treatment Rabipur and Encepur, used for the prevention of tick-borne encephalitis, by the British drugmaker includes milestone payments of up to 495 million euros. Reporting by Aakash Jagadeesh Babu in Bengaluru; Editing by Arun Koyyur Our Standards:The Thomson Reuters Trust Principles.

Oct 21

FDA approves AstraZeneca diabetes drug for treating heart failure risk

FILE PHOTO: The company logo for pharmaceutical company AstraZeneca is displayed on a screen on the floor at the New York Stock Exchange (NYSE) in New York, U.S., April 8, 2019. REUTERS/Brendan McDermid/File Photo (Reuters) – AstraZeneca’s diabetes drug Farxiga has been approved for use in the United States as a treatment to reduce the chances of hospitalisation for heart failure in adults with type-2 diabetes and other cardiovascular risks, the British drugmaker said on Monday. The approval by the U.S. Food and Drug Administration is based on results from the DECLARE-TIMI 58 clinical trial, the London-listed company said, and follows a similar approval here by the European authorities in August. Farxiga is the first of its class to be approved in the United States for this indication, Ruud Dobber, executive vice president of BioPharmaceuticals at AstraZeneca said. “This is … Continue reading

Oct 20

Roche immunotherapy cocktail boosts survival in liver cancer

FILE PHOTO: Swiss drugmaker Roche’s logo is seen at their headquarters in Basel, Switzerland January 28, 2016. REUTERS/Arnd Wiegmann/File Photo ZURICH (Reuters) – Roche’s Tecentriq immunotherapy mixed with the older cancer drug Avastin lifted both overall survival and progression-free survival in people with liver cancer that cannot be surgically removed, the Swiss drugmaker said on Monday. The company said it plans to submit the data to health authorities including the U.S. Food and Drug Administration, the European Medicines Agency and the China National Medical Products Administration, in hopes of a speedy approval in this new indication. Reporting by John Miller Our Standards:The Thomson Reuters Trust Principles.

Oct 20

Erdogan says he will never allow vaping, will block e-cigarettes in Turkey

FILE PHOTO: U.S. Vice President Mike Pence (not pictured) meets with Turkish President Tayyip Erdogan at the Presidential Palace in Ankara, Turkey, October 17, 2019. REUTERS/Huseyin Aldemir ANKARA (Reuters) – Turkish President Tayyip Erdogan said on Sunday he will never allow electronic cigarette companies to produce their products in Turkey, urging Turks to drink tea instead. Speaking at an event against smoking in Istanbul, Erdogan said he had ordered his Trade Minister “never” to allow e-cigarettes in Turkey and said that tobacco companies were “getting rich by poisoning” people. “They asked us for a place and permission to produce these (e-cigarettes). We didn’t give it to them and we will not,” he said, without saying which firm or firms he was referring to. “They want to invest in Turkey…Go and make your investment elsewhere.” Around 27% percent of Turkey’s total … Continue reading

Oct 20

Stigma and Mental Illness

Stigma and Mental Illness

This innovative video is a joint project of the IWK Health Centre and the Mental Health Commission of Canada (MHCC). It was designed to help combat the stigma attached to mental illness and will be used to educate health care providers and hospital staff across the country who work with children and youth.

Oct 20

James Allison’s Cancer Research Breakthrough

James Allison’s Cancer Research Breakthrough

Nearly two decades ago, researcher James Allison found a way to use the body’s own immune system to kill malignant cells, a discovery that’s transforming cancer treatment and saving lives. Photo: Michael Stravato for The Wall Street Journal Subscribe to the WSJ channel here: http://bit.ly/14Q81Xy Visit the WSJ channel for more video: https://www.youtube.com/wsjdigitalnetwork More from the Wall Street Journal: Visit WSJ.com: http://online.wsj.com/home-page Follow WSJ on Facebook: http://www.facebook.com/wsjlive Follow WSJ on Google+: https://plus.google.com/+wsj/posts Follow WSJ on Twitter: https://twitter.com/WSJLive Follow WSJ on Instagram: http://instagram.com/wsj Follow WSJ on Pinterest: http://www.pinterest.com/wsj/ Follow WSJ on Tumblr: http://www.tumblr.com/tagged/wall-street-journal Don’t miss a WSJ video, subscribe here: http://bit.ly/14Q81Xy More from the Wall Street Journal: Visit WSJ.com: http://www.wsj.com Visit the WSJ Video Center: https://wsj.com/video On Facebook: https://www.facebook.com/pg/wsj/videos/ On Twitter: https://twitter.com/WSJ On Snapchat: https://on.wsj.com/2ratjSM

Oct 19

Nada Surf “Cold To See Clear” (Official Video)

Nada Surf “Cold To See Clear” (Official Video)

The official video for Nada Surf’s “Cold To See Clear” from their album ‘You Know Who You Are’. Available on Barsuk Records (US/Canada) and City Slang (Europe) on March 4, 2016. Pre-Order Now At: City Slang – http://smarturl.it/YKWYAlabel iTunes – http://smarturl.it/YKWYAiTunes Amazon – http://smarturl.it/YKWYAamazon Stream – http://smarturl.it/YKWYAstream Produced and Directed by Spencer Gentz http://spencergentz.com http://www.nadasurf.com

Oct 19

The Wiggles – The Allergy Song

The Wiggles – The Allergy Song

The Wiggles Allergy Song! As a website dedicated to providing easy, safe & nutritious recipes for multiple food allergies and special diets, we applaud the Wiggles in raising awareness of this very serious issue. Michelle and Pauline of http://www.theallergymenu.com

Oct 18

Opioid settlement talks fail, landmark trial expected Monday

CLEVELAND (Reuters) – A landmark trial over the U.S. opioid epidemic is on track to begin on Monday after drug companies and local governments failed to agree on a settlement on Friday that had been expected to be valued at around $50 billion. A view of the statue standing in front of the U.S. District Courthouse in Cleveland, Ohio, U.S., October 18, 2019. REUTERS/Aaron Josefczyk Top executives of the largest U.S. drug distributors and drugmaker Teva Pharmaceutical Industries Ltd left a Cleveland courthouse on Friday and lawyers for states and thousands of local governments said there was no agreement. The parties and four state attorneys general had been summoned by U.S. District Judge Dan Polster, who could be seen on Friday shuttling between the groups in separate rooms. Paul Hanly, a lawyer for local governments that brought the bulk of … Continue reading

Oct 18

FDA approves Alexion's Ultomiris for another rare blood disease

(Reuters) – The U.S. Food and Drug Administration on Friday approved Alexion Pharmaceuticals Inc’s treatment for a second rare blood disorder, the company said. The treatment, Ultomiris, has already been approved in the United States, Japan and the European Union to treat adults with blood disorder called paroxysmal nocturnal hemoglobinuria. Friday’s approval allows its use in treating atypical hemolytic uremic syndrome (aHUS), a condition that causes abnormal blood clots to form in small blood vessels in the kidneys, which could result in kidney failure. The label for the treatment carries a boxed warning, the FDA’s harshest, flagging risks of life-threatening meningococcal infections or sepsis, that have occurred in patients treated with Ultomiris. The FDA approval is a shot in the arm for the drugmaker, which has been pushing to expand Ultomiris’ label as U.S. market exclusivity for its best-selling drug, … Continue reading

Oct 18

Opioid settlement talks fail, landmark trial expected Monday: attorney

CLEVELAND (Reuters) – A landmark trial over the U.S. opioid epidemic is on track to begin on Monday after drug companies and local governments failed to agree on a settlement on Friday that had been expected to be valued at up to $50 billion. A view of the statue standing in front of the U.S. District Courthouse in Cleveland, Ohio, U.S., October 18, 2019. REUTERS/Aaron Josefczyk Top executives of the largest U.S. drug distributors and drugmaker Teva Pharmaceutical Industries Ltd were seen leaving a Cleveland courthouse on Friday and a lawyer for thousands of local governments said they failed to reach a deal. The parties and four state attorneys general had been summoned by U.S. District Judge Dan Polster who has long hoped to get a settlement. Polster could be seen on Friday shuttling between the groups in separate rooms. … Continue reading

Oct 18

J&J recalls 33,000 bottles of baby powder as FDA finds asbestos in sample

(Reuters) – Johnson & Johnson (JNJ.N) said on Friday it is recalling around 33,000 bottles of baby powder in the United States after U.S. health regulators found trace amounts of asbestos in samples taken from a bottle purchased online. J&J shares fell more than 6% to close at $127.70. The move marks the first time the company has recalled its iconic baby powder for possible asbestos contamination, and the first time U.S. regulators have announced a finding of asbestos in the product. Asbestos is a known carcinogen that has been linked to deadly mesothelioma. The recall is the latest blow to the more than 130-year-old U.S. healthcare conglomerate that is facing thousands of lawsuits over a variety of products, including baby powder, opioids, medical devices and the antipsychotic Risperdal. A jury last week ordered the company to pay $8 billion … Continue reading

Oct 18

Early life stress tied to increased pain sensitivity later

(Reuters Health) – People who were exposed to more sources of stress in the womb and early childhood may be more sensitive to pain by early adulthood than their counterparts with little or no exposure to stress early on, a recent study suggests. Researchers focused on stressful life events that might occur in children’s households during pregnancy or early childhood such as pregnancy complications, the death of a close friend or family member, marital problems or breakups, job loss or other financial hardships, or residential moves. Then, researchers tested pain sensitivity for 1,065 participants when they reached 22 years old. “Significant life stress is known to result in changes to the body’s biological systems partially by modifying gene expression,” said Rob Waller, lead author of the study and a researcher at Curtin University in Perth, Australia. Stress can start processes … Continue reading