Aug 26

atropine eye drops

What is atropine, and how does it work (mechanism of action)? Atropine occurs naturally and is extracted from belladonna alkaloids contained in plants. Atropine blocks the action of acetylcholine, a neurotransmitter that causes the contraction of two types of muscle, smooth and cardiac muscles. It also has other neurological effects. Ophthalmic atropine is used during eye examinations to dilate the pupil. Atropine is also used to weaken the contraction of the muscles within the eyes, both the muscles that operate the iris and the lens. Paralysis of the lens, called cycloplegia, results in the loss of the ability to focus vision. Paralysis of the iris (mydriasis) prevents the iris from adjusting to the brightness of incoming light and affects the ability to see clearly. In clinical studies, use of a single topical administration of atropine 1% ophthalmic solution (eye drops) … Continue reading

Aug 22

Smoggy Air Might Contribute to Macular Degeneration

Latest Eyesight News WEDNESDAY, Aug. 21, 2019 (HealthDay News) — Tailpipe pollution might pose a real health threat to aging eyes, according to a new study out of Taiwan. Researchers there found that exposure to high levels of two car exhaust pollutants nearly doubled the odds of age-related macular degeneration (AMD). It’s one of the most common causes of vision loss in older people. The study is the first of its kind to “demonstrate a significant association between AMD and high levels of ambient” nitrogen dioxide and carbon monoxide in the air people breathe, said a study team led by Suh-Hang Hank Juo. He’s a professor at the Graduate Institute of Biomedical Sciences at China Medical University in Taichung. One U.S. expert who reviewed the findings said they highlight a growing threat to people’s vision. “With the ever-increasing industrialization of … Continue reading

Aug 15

How to Relieve Dry, Irritated Eyes

By Len CanterHealthDay Reporter Latest Eyesight News THURSDAY, Aug. 15, 2019 (HealthDay News) — Do all the ads for dry eye relief have you thinking you could have this condition? If you’ve ever felt like you had a grain of sand in your eye when nowhere close to the beach, you could be experiencing dry eye. Exactly what is dry eye? Simply put, it’s when you aren’t making enough tears to keep the front surface of the eye lubricated, or your tears don’t have enough water in them. Eyes can feel gritty, scratchy or like they’re burning. You might even notice excess watering or blurred vision. Tear production often lessens with age, but it can also be the result of a medical condition — not only eye diseases but also rheumatoid arthritis, diabetes and thyroid problems. It can also be … Continue reading

Aug 09

betaxolol ophthalmic (Betoptic S, Betoptic)

What is betaxolol ophthalmic, and how does it work (mechanism of action)? Betaxolol is a beta-adrenergic blocking agent that is used for the treatment of glaucoma. When taken by mouth, betaxolol and other beta-adrenergic blocking agents act mainly by blocking the action of the sympathetic (adrenergic) nervous system, for example, on the heart. In addition to its effect on the heart, betaxolol reduces the pressure within the eye (intraocular pressure). This effect is thought to be caused by reducing the production of the liquid (called the aqueous humor) within the anterior chamber of the eye although the precise mechanism of its effect is not known. The reduction in intraocular pressure reduces the risk of damage to the optic nerve and loss of vision in patients with elevated intraocular pressure due to glaucoma. Betaxolol was approved by the U.S. Food and … Continue reading

Aug 05

Trachoma

Trachoma facts Trachoma is the leading infectious cause of blindness in the world. Trachoma is a contagious and potentially blinding infectious eye disease. The World Health Organization classified trachoma as one of the neglected tropical diseases and the leading infectious cause of blindness in the world. Blindness from trachoma may be preventable by screening and treatment with antibiotics and surgery. What is trachoma? Is trachoma contagious? Trachoma is a contagious bacterial infection that affects the surface of the eyes. Over time, scar tissue or ulcers can form that lead to blindness. Currently around 1.9 million people worldwide are blind or visually impaired by trachoma, and it remains a public health problem in 44 countries. It spreads when bacteria in the secretions from the eyes of an affected individual extend to others either by person-to-person contact or by eye-seeking flies, particularly … Continue reading

Aug 05

Trouble Driving At Night? Yellow Lenses Won't Help

By Amy NortonHealthDay Reporter Latest Eyesight News FRIDAY, Aug. 2, 2019 (HealthDay News) — “Night-driving” glasses that promise to dim the glare of headlights may not work as advertised, a new study finds. The glasses, featuring yellow-tinted lenses, have been marketed for years as a way to ward off blinding headlights and make night driving easier. The problem: There’s no scientific evidence they work. Now a new study, published online Aug. 1 in JAMA Ophthalmology, offers a buyer-beware message. In driving simulation tests, researchers found that yellow lenses did not improve people’s performance over clear lenses — including when they were faced with oncoming headlights. “When you wear a colored lens, you cut off a chunk of light,” explained lead researcher Alex Hwang of the Schepens Eye Research Institute at Massachusetts Eye and Ear, and Harvard Medical School in Boston. … Continue reading

Aug 02

antipyrine and benzocaine otic (Auralgan, Aurodex – removed from market)

What is antipyrine and benzocaine otic (Auralgan, Aurodex – discontinued)? Antipyrine/benzocaine is a combination product used for cleaning the ear canal and for treating middle ear infections. It reduces pressure, congestion, inflammation, pain, and discomfort in the ear. What brand names are available for antipyrine and benzocaine otic (Auralgan, Aurodex – discontinued)? On July, 2, 2015 the FDA asked all manufacturers of antipyrine and benzocaine otic products (Auralgan and Aurodex brand names) to stop selling these products because they have not been proven to be safe and effective. Is antipyrine and benzocaine otic (Auralgan, Aurodex – discontinued) available as a generic drug? Yes Do I need a prescription for antipyrine and benzocaine otic (Auralgan, Aurodex – discontinued)? Yes What are the uses for antipyrine and benzocaine otic (Auralgan, Aurodex – discontinued)? Octic antipyrine and benzocaine is used for cleaning earwax … Continue reading

Aug 01

timolol ophthalmic solution (Timoptic)

What is timolol ophthalmic solution, and how does it work (mechanism of action)? Timolol is a beta-adrenergic blocking agent. Like other beta-adrenergic blocking agents, it mainly blocks the action of the sympathetic (adrenergic) nervous system, for example, on the heart. In addition to its effect on the heart, timolol causes a reduction of the pressure within the eye (intraocular pressure). This effect is may result from a reduction in production of the liquid (aqueous humor) within the eye. The precise mechanism of this effect is not known. The reduction in intraocular pressure reduces the risk of damage to the optic nerve and loss of vision in patients with glaucoma. Timolol was approved by the FDA for ocular use in 1978. What brand names are available for timolol ophthalmic solution? Timoptic, Timoptic-XE, Timoptic in Ocudose Is timolol ophthalmic solution available as … Continue reading

Jul 31

Retinitis Pigmentosa

How do doctors diagnose retinitis pigmentosa? Because there are so many variants of RP with different symptoms and signs, the diagnosis may not be straightforward at first. Certain clues in the patient’s history (especially retinitis pigmentosa in family members) and complaints (such as difficulty with adapting to the dark) may make one suspect RP. On dilated eye examination, the ophthalmologist may find characteristic clumping of pigment in the retina (a pattern described as bone spicules). This is due to changes in the retinal pigment epithelium, a layer of cells found under the receptors. Other characteristic findings include narrowed retinal arterioles and a waxy appearance of the optic nerve. Other non-RP eye diseases can show similar patterns in the retina (for example, Kearns-Sayre syndrome and congenital syphilis). Therefore, it may be necessary to perform additional testing to confirm the diagnosis of … Continue reading

Jul 31

Coats Disease

What is Coats disease? Eye doctors can usually diagnose Coats disease during a routine eye exam. Coats disease is a rare condition in which abnormal blood vessels in the retina dilate and leak fluid, resulting in damage to the retina and possibly vision loss. It most often appears at 8-10 years of age, affects males three times more often than females, and usually affects only one eye. The cause is unknown, and it does not appear to be hereditary. The retina is the light-sensing layer of tissue in the back of the eye. In Coats disease, small retinal arteriole and capillary vessels become “telangiectatic,” widening and dilating, forming small aneurysms that resemble tiny light bulbs. These vessels leak both fluid and fats, which build up in and under the retina. In advanced cases, the fluid accumulation is large enough to … Continue reading

Jul 26

First U.S. Trial Using CRISPR Within the Body Is Set to Begin

FRIDAY, July 26, 2019 (HealthDay News) — In a U.S. first, a clinical trial to begin this fall will use the inside-the-body gene-editing technique CRISPR to try to cure illness. Doctors hope to use the cutting-edge technique to cure a type of inherited form of blindness called Leber congenital amaurosis. Latest Eyesight News Even though they have normal eyes, patients with this type of blindness lack a gene that turns light into signals to the brain that enable sight, the Associated Press reported. Using a tool that cuts or “edits” DNA in a specific spot, researchers will attempt to give child and adult patients a healthy version of the gene they lack. The trial will include 18 people across the United States and will be conducted by two companies, Editas Medicine and Allergan. Leber congenital amaurosis is the most common … Continue reading

Jul 22

Sunglasses a Shield for the Eyes

Latest Eyesight News SATURDAY, July 20, 2019 (HealthDay News) — Sunglasses need to be more than just fashion accessories, an eye expert advises. “Think of sunglasses as sunscreen for your eyes,” said Dr. Dianna Seldomridge, clinical spokesperson for the American Academy of Ophthalmology. “Your eyes need protection from the sun’s damaging ultraviolet rays, just like your skin,” she explained. “Make sure your eyes are protected year-round. Harmful UV rays are present even on cloudy days.” You should choose sunglasses that block 99% to 100% of both UVA and UVB radiation from the sun. You may be confused by labels that say the sunglasses provide 100% protection from UVA/UVB radiation, while others offer 100% UV 400 protection. Both will block 100% of the sun’s harmful radiation, the academy said in a news release. If you’re skeptical of the UV protection label … Continue reading