felodipine, Plendil

February 25, 2015 − by Contributor − in Archived − Comments Off on felodipine, Plendil

felodipine, Plendil


Pharmacy Author:

Medical and Pharmacy Editor:

GENERIC NAME: felodipine

DISCONTINUED BRAND: Plendil

DRUG CLASS AND MECHANISM: Felodipine is an oral calcium- channel
blocker (CCB) of the dihydropyridine (DHP) class. Other calcium channel blockers
in the DHP class include nifedipine (Procardia, Adalat), amlodipine (Norvasc),
nisoldipine (Sular), nicardipine (Cardene), and isradipine (Dynacirc). Calcium
is necessary for muscle cells to contract. Felodipine prevents calcium from
being released within the muscle cells of the small arteries and thereby causes
the muscles to relax and the arteries to dilate or expand. Dilation of arteries
reduces blood pressure. Felodipine has little or no effect on the muscles of
veins or the heart. Felodipine was approved by the FDA in 1991.

PRESCRIBED FOR: Felodipine is used to treat high blood pressure. It
may be used alone or in combination with other drugs. Felodipine also is used to
treat patients with angina although it is not FDA approved for this use.

Medically Reviewed by a Doctor on 2/24/2015

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